The Phospho-EGFR-Y1172 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to EGFR, egfra, epidermal growth factor receptor, ERBB, ERBB1, Errp, and HER1. This antibody recognizes Human antigen. The Phospho-EGFR-Y1172 Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene